About Monoclonal Antibodies

Monoclonal antibodies are derived from cells that are identical because they are cloned from a single cell and then replicated. They are produced from animal tissue, most commonly laboratory mice. Humanized monoclonal antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibodies produced naturally in humans. All monoclonal antibodies end with "mab," and a number have shown promise in MS.